Alternative cancer treatment center california

Fractionated Chemotherapy With Biological Response Modifier

Fractionated Chemotherapy With Biological Response Modifier

What is FCBRM?

Fractionated Chemotherapy with Biological Response Modifier, known as FCBRM, is an incredibly effective and safe form of low-dose chemotherapy that many integrative doctors give their patients to shrink a tumor mass.

FCBRM can prove massively beneficial in lieu of traditional chemo treatments. The research and clinical applications of FCBRM were developed in 1930 and have been used by integrative cancer doctors since 1946, so it is not a new therapy, and many studies have proven its effectiveness.

For instance, one study on breast cancer patients at George Washington University found that using insulin, along with the breast chemotherapy drug methotrexate, increased the killing effect of the methotrexate by a factor of 10,000.

FCBRM is excellent because patients experience few to no side effects from it.  So unlike patients that do full-dose chemotherapy, those with IPTLD don’t experience hair loss, vomiting, or other side effects. At Cancer Center for Healing, our patients maintain a high quality of life during IPT treatment, which is very gentle, safe, and effective.

This simple medical procedure involves intravenously administering the hormone insulin to the body, followed by glucose and various anti-cancer agents. For this procedure, we use 1/10th of the traditional chemotherapy dose, using specific anti-cancer agents that test best for each patient, according to RGCC testing.

How does FCBRM Work?

Cancer cells have ten times more insulin receptors on their surface than regular cells. Insulin is a hormone that your body uses to shuttle glucose into the cells.

So when you give your body insulin, along with glucose, the insulin acts as a “Trojan horse” or an escort, to more effectively bring not only glucose but also the anti-cancer agents into the cancer cells. Since cancer cells love sugar, they readily open up their insulin receptors and “eat” the glucose, along with chemotherapy drugs and/or natural anti-cancer agents.

Insulin also helps the body to fight cancer because it prompts cancer cells to divide, which is when they are most vulnerable to being destroyed by drugs and other anti-cancer agents. Experts believe that insulin does this during what is called the “therapeutic moment”— when your blood sugar has been lowered enough for the chemotherapy to be administered most effectively.

Because normal cells don’t have as many insulin receptors as cancer cells, they don’t absorb very much of the glucose or the chemotherapy agents, which means that patients aren’t likely to suffer severe side effects from it.

Used by integrative physicians worldwide since the 1930s, FCBRM is an advantageous protocol that utilizes insulin to make cancer cells more sensitive and receptive to chemotherapy agents.

This allows medical practitioners to administer lower chemotherapy doses, reduce toxicity levels, and preserve the patient’s quality of life, all without compromising treatment results.

The type of agent used depends on the outcome of the patient’s results from RGCC testing. Insulin is used as cancer cells have 10x more insulin receptors than a regular cell and, therefore, will attract glucose and chemotherapy drugs. Only a 10% dose is used because FCBRM treatment targets cancer cells.

Benefits of FCBRM

FCBRM has been reported among some integrative doctors to work especially well for breast, prostate, lung, colon, bladder, uterine, and stomach cancers, as well as for lymphomas, sarcomas, and melanomas.

There are even reports that FCBRM has caused people with very difficult cancers, such as pancreatic, ovarian, and renal cell cancers, to go into remission. Other cancers that respond well to FCBRM include blood, bone, cervical and esophageal cancers.

Unlike traditional full-dose chemotherapy, FCBRM produces few to no side effects. Some patients become slightly anemic or tired from it, but in general, most tolerate it well. The chemotherapeutic agents are then given in much lower doses than in conventional therapies because of this insulin effect.

FCBRM can also deliver chemotherapeutic drugs more frequently, also thought to allow a therapeutic impact, which can be augmented by synchronic applied hyperthermia, while imparting fewer side effects and allowing patients a higher quality of life.

This method has almost none of the usual side effects of chemotherapy, such as nausea and hair loss, so it is appealing to individuals who recognize their need for treatment but want to conduct it in a more gentle manner.

It has been reported to work well with many types of cancers. In fact, some physicians have reported how FCBRM helps patients with very challenging cancers. Patients should know, however, that each individual is different and responds to treatments in different ways.

FCBRM cancer treatment is administered through an IV, the same way as conventional chemotherapy. Patients begin the process by relaxing in a comfortable reclining chair and the treatment may take between 60 – 90 minutes. Once the insulin is given, chemotherapy drugs are then applied in small doses.

This in turn allows medical practitioners to reduce toxicity levels and helps preserve the patient’s quality of life, all without compromising treatment results.

FCBRM in combination with hyperthermia, can be very tough on tumors, while it is regarded by us to be more gentle for the patient. Patients generally may continue to live a normal lifestyle while being treated.

Using insulin allows us to differentiate the cancer cell population from the normal cell population. That means a lower dose of chemotherapy can be used and this is important since these drugs have considerable toxicity associated with them.

FCBRM reduces chemotherapy side effects in normal cells.

The so-enhanced chemotherapy combined with hyperthermia kills cancer cells more effectively. A 1981 study found that using insulin increased the killing effect of the chemo drug methotrexate by a factor of 10,000, for example, and there are also numerous showing, that chemotherapy is augmented by heat.

This gentle treatment allows also the use of complementary therapies to strengthen the immune system, it is our body’s best natural defense against the return of cancer.

FCBRM and low dose chemotherapy treatment costs are significantly less than conventional cancer therapies.

Call (949) 581-HOPE (4673), email us at , or chat with us live to schedule your appointment. We are here to answer any questions and to help you schedule a personal consultation with an Integrative Cancer Specialist.


[i] Alabaster, A; Vonderhaar, B; Shafie S. “Metabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells.” Eur J Cancer ClinOncology, (1981): Vol. 17:11, 1223–1228.

We understand how stressful life can get when a person has been diagnosed with cancer. At Cancer Center for Healing, we pledge to accompany you throughout your healing journey.


It is impossible to design a single cancer treatment that is effective against all types of cancers. For this reason, Cancer Center for Healing uses a combination of integrative and complementary cancer treatments for customized IV Therapy programs designed to shrink primary tumors, slow the growth of tumors, and eliminate cancer cells that have spread to other parts of your body.

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